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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

今年的获奖榜单如下:
Ahead of the release, economists at ANZ said they expected inflation to pick up in January owing to rising food prices, and the low commodity prices would weigh on the CPI.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

The EU’s Americas gambits
But a friend saw a TV report about it and contacted the sorting office. Mr Siddeeq, 74, says he is still eager to read it, despite now being divorced。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

第三,麦克德莫特可以作为一道保险,以防如果今年夏天安德烈-罗伯森选择自由离开时雷霆无人可用。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

我不了解你是什么样的情况,但是如果我根据工作,生活和生活各自准备一个日历,我会手忙脚乱的。如果你生活中所有的事都记在一个日历上,在一个计划中,你就不能重复安排任何事了,就像一个重要的测试或者和老板的晚餐一样。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

General Motors is helping fuel the improved jobs outlook in the Grand Canyon State. In March, the automaker announced plans to build the company’s fourth Information Technology Innovation Center in Phoenix suburb Chandler. GM is expected to hire 1, 000 workers, mainly consisting of software developers, database administrators and systems analysts for the new center. “The greater Phoenix area is a fantastic hub of emerging technical talent – from university graduates to working professionals, ” said GM CIO Randy Mott in a release announcing the move.
乔斯·威登一直都很喜欢科幻小说,也是西部小说的忠实拥趸。尽管这两种小说类型风马牛不相及,但是从《天使杀手》这部书中,他找到了一种方式,可以把二者融合起来。"我当时想把新垦地的概念好好地演绎一下",他说,"人类文明是由那些被历史深深伤害了的人们推动前行的,而不是那些创造历史的伟人。"这一次,威登决定把新垦地从西部搬到了"宁静号"宇宙飞船上。
不过,在这一反弹中也出现了奖金数额的下滑:去年的平均年终奖是12821元人民币(合1861美元),比2015年多了大约2000元人民币,却仍比2014年的平均值少了800元人民币。在奖金缩水的被调查者中,逾四分之一的人将原因归结为公司业绩太差。
Julia Hartz

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

公众宗教研究机构与宗教新闻通讯社联合开展的这项调查显示,不同政治派别和不同宗教信仰的人们对于恶劣天气的观念存在分歧,今年已经发生了多起严重的高温和干旱灾害。
9.消防员
泰勒·斯威夫特《名誉》
There are many more 2016 movie releases that will do well at the box office, but there are only a few that we're all eagerly waiting to watch.

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

No. The Bank of Japan’s life will get tougher in 2018 as the US Federal Reserve tightens policy and widens the interest rate gap with Japan. But governor Haruhiko Kuroda is determined to hike rates in response to one thing only: inflation. The BoJ may let the yield curve climb a little if prices start to accelerate, but real interest rates in Japan will end 2018 no higher than at the start of the year.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

单词intended 联想记忆:

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

他会在自己的独唱专辑中尝试什么样的歌曲呢:《Sweet Creature》(《可爱的人儿》)和《Ever Since New York》(《自从来到纽约》)是温馨的原声抒情歌曲;而在《Kiwi》(《奇异果》)这首歌中,他大声地炫耀着自己的欢乐;《Two Ghosts》(《两只幽灵》)则是一首为分手而惋惜的歌曲。
STEP 3: PRACTICE CREEPY LOOKS

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 浙江特色小镇海外推广展走进巴黎
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Artificial pancreas, however, knock insulin into your body automatically. The device looks much like a regular insulin pump, which slips you insulin continuously through your skin, but this one monitors your blood sugar at all times and adjusts itself accordingly. So even when the wearer sleeps, there's no danger of falling into shock if their sugar drops too low.
为提高中国足球在国际赛场上的竞争力,中国政府日前公布了最新的足球发展计划,将在2017年开设20000所足球专业学校,用于训练年轻球员、培养人才。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

8.Please aid the Olympic authorities and organisers by demonstrating at all times that you are not a terrorist. Do not perspire, take off your shoes, smile in a weird way while texting someone, or point and shout: "Hey! Look at all those missiles on that roof over there!" In fact, if you're not using your hands for anything, it's probably best if you keep them in the air where everybody can see them.
推动社会治理创新。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

['ru:m?]
In 2010, the Martin Aircraft Company introduced a jetpack it called "the world's first piratical jetpack." The jetpack even won a spot in Time's Top 50 Inventions of 2010. While its development has been on since 1981, the world's first jetpack is known to have flown in 1958. It was designed by Wendell Moore, a researcher at Bells Aerosystems. Early prototypes of Wendell's jetpack could reach a height of 5 meters (16 ft) and remain airborne for three minutes. This attracted the attention of the US Army, which funded the project with $150,000. Several test flights were later done for the US Army and even for JFK himself. The army later stopped paying for more research into the project because the flight time and distance were not convincing enough. NASA also wanted to use the jetpack for their Apollo 11 mission to serve as backups in case their lunar module malfunctioned. They later changed their minds, going for the lunar rover instead. After this setback, Bell discontinued further research on the jetpack.
Yet if “Mad Men” showed us anything (besides how cool a skinny suit could look, and that wide ties really were not a good men’s wear moment), it is that the decade chronicled was a complicated, often unhappy, occasionally destructive time.
I do not see much evidence that radical “managerless” models such as “Holacracy” will catch on. But more companies will realise that if they constantly test innovative ways forward — as start-ups do — they will be more flexible and decisive than old-style bureaucracies and meritocracies.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 下半年楼市猜想:“大稳小乱”
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

Usually sober-minded analysts, accustomed to the auto industry’s slow growth, seem to shed their inhibitions when it comes to Tesla. Rod Lache of Deutsche Bank has attached a $310 price target on the stock. Not to be out-done, Adam Jonas of Morgan Stanley established a $320 price target and calls Tesla it the “most important car company in the world”.

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

The list has four British universities, which are Cambridge, Oxford and London's University College and Imperial College. The University of Tokyo is also included in top 20.
Summly attempts to solve this problem by creating “snapshots” of stories that allow readers to browse more quickly than reading full articles. The app will close down but Mr D’Aloisio’s technology will be integrated into Yahoo’s mobile apps.

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Consider this: Will the experience enhance your knowledge and play to your strengths? Will it introduce you to new concepts and new people? (All great reasons to say yes!) Will it require you to develop new techniques for managing your team or working with more experienced people? Embrace this challenge and get out of your comfort zone.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

“现在黑客使用流行文化或体育活动中的常见说法来破解网上账户,因为他们知道很多人在使用这些容易记住的词做密码。”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Writing for a Comedy Series: Aziz Ansari and Alan Yang, “Master of None” (“Parents”)
这个位于非洲西南部的国家拥有20多家国家公园以及世界上最古老的沙漠。
The new numbers, reported by a tracking initiative called the Global Carbon Project and published in the journal Nature Geoscience, came on the eve of a United Nations summit meeting meant to harness fresh political ambition in tackling climate change. Scientists said the figures showed that vastly greater efforts would be needed to get long-term global warming within tolerable limits.
White anxiety has fueled this year’s political tumult in the West: Britain’s surprising vote to exit the European Union, Donald J. Trump’s unexpected capture of the Republican presidential nomination in the United States, the rise of right-wing nationalism in Norway, Hungary, Austria and Greece.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

"This year's prize concerns a central economic problem: how to match different agents as well as possible," the academy said.
根据美国影院业主协会的数据显示,2015年全球影院收益达383亿美元创新高,中国贡献了68亿美元的票房收入,较上一年增长了近五成。
minutes
学会控制自己的情绪,控制自己的想法,克服对被拒绝的恐惧,学会向别人敞开心扉。
《盗墓笔记》

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
From the themed collection: 家具电商为何屡中“电伤”
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

[?'fektid]
“We have not really assumed China will get better in the rest of the year,” said James Quincey, Coca-Cola’s chief operating officer. He said juice sales fell double digits in the second quarter in the country and Coca-Cola drinks dropped single digits.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

?Bond has it all and that's exactly what the most beautiful women demand in the men they date. Women who really enjoy sex prefer "bad boys" -- and there's no doubt 007 qualifies. Feminine women prefer masculine men. And for one night stands women look for physical attractiveness and dominance -- which Bond has in spades.

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Two against-the-clock tours of Los Angeles. Two celebrations of the sometimes prickly solidarity among women. Four tremendous performances, from Kitana Kiki Rodriguez, Mya Taylor, Julia Garner and the great Lily Tomlin. “Grandma” is the work of a studio veteran. “Tangerine” was shot on iPhones. Anyone prone to lamenting the death of movies needs to shut up and watch these.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

n. 商业广告
尽管看起来有着大量的目标核对工作,但在5月7日,中国驻贝尔格莱德的大使馆却被从美国空军B-2幽灵轰炸机上发射的五枚卫星制导联合直接攻击弹药击中。三名中国记者——新华社记者邵云环,光明日报记者许杏虎和他的妻子朱颖在袭击中身亡。另外20名中国公民受伤5人伤势严重。
2016的很多电影都会有很好的票房号召力,但人们迫不及待想要观看的其实只有那么几部。
adj. 傲慢的,自大的

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

今年的获奖榜单如下:
Her mother discovered the debits on Jan 30, China Central Television reported.
Leading the pack of the best airlines for holiday travel is Hawaiian Airlines, followed by another Pacific Coast-focused carrier, Alaska Airlines. Conversely, the worst airline for holiday travel is New York-based JetBlue Airways, with ExpressJet, a regional carrier, coming in next to last, according to the FlightAware data.
Stand: Apple CEO Tim Cook fought for workplace protection for the LGBT community

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
From the themed collection: 海外购房“热” 你跟风了吗?
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

vt. 挖去果核
Mr Lam predicts that any recovery in the market will rely on appetite from cash-rich companies from mainland China, with foreign investors restricting their investments to real estate investment trusts or stocks exposed to developers, rather than actual property.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Pete Rossi can count on one hand the number of weeks out of the year that he works more than 50 hours. But the rest of the year, his job as an actuary with the Department of Defense, provides a good living with a minimum of stress.
5.3-D 打印耳朵
在纽约市许多公寓楼的大门背后,充斥着居民们不协调的抱怨声。从我的“房地产答疑”(Ask Real Estate)专栏所收到的抱怨信中,我们可以一窥居民们是如何应对生活在拥挤、昂贵的住房中的种种不顺心的。比方说,有个合作公寓的股东被邻居家的老鼠窝吓坏了;有一对父母被禁止将婴儿车推进楼内的电梯;有个租户厨房里的橱柜从墙壁上掉了下来。
今年1月3日春节假期车票开售以来,约有2.8亿张火车票是在12306网站上售出的。
amnesty

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 做好预调微调 确保稳中向好
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Belmonte's 1950 ticket will be displayed at a Zurich museum that is set to open in 2015, according to Jerome Valcke, FIFA's secretary general. "This is something rare we would like to have for the museum," he said.
At least 120 million American voters had been expected to cast votes in the race between the Democratic incumbent and Romney after a campaign focused on how to repair the ailing U.S. economy。
公司一直都在寻求省钱的办法,将一些自由职业者能胜任的工作外包出去。虚拟助理可以做许多全职员工可以做的工作,但是忠诚度却比较低。这些员工可以帮助拓展商业渠道,或者促进事情更加顺利进行。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

创业者都是行动者和颠覆者。他们不能去分析每一个细节,否则他们将寸步难行。初创公司没有拖延的资本。创业是一个全天候、无休假的职业,创业者必须具备持久不变的前进动力。迈出每一步的时候进行简单的评估,然后继续前进。相信自己的直觉。
A Times reporter, Denise Grady, went inside an operating room to observe an experimental technique to treat severe spina bifida in a 24-week-old fetus. The doctors performing the surgery hope it will result in superior outcomes for children born with the disorder. Their first 28 surgeries have seen good results so far. Jan. 14 is the due date for the mother who was the subject of the article.

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The UK’s Warwick Business School recorded the best progression at the top, moving up from 16th to ninth place, while the Shanghai Advanced Institute of Finance (Saif), based at JiaoTong University, enjoys the bestprogression overall, jumping from 28th to 14th place.
8. Your appendix might not be a useless evolutionary byproduct after all. Unlike your wisdom teeth, your appendix might actually be serving an important biological function - and one that our species isn't ready to give up just yet.
格温妮丝·帕特罗(Gwyneth Paltrow)曾出演《莎翁情史》(Shakespeare in Love)获最佳女主角奖,并成为好莱坞明星。为了避免在发表获奖感言时出现混乱,她却把小金人藏了起来,因为“这东西吓坏我了”。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Imports grew 3.1 per cent year-on-year in dollar terms to $168.6bn in December after growing a revised 4.7 per cent (previously 6.7 per cent) the previous month. That rate was roughly in line with a median forecast of 3 per cent growth.
马修?麦康纳(Matthew McConaughey)和贾里德?莱托(Jared Leto) 均凭在剧情片《达拉斯买家俱乐部》(Dallas Buyers Club)中的真实演绎荣获金球奖,该片讲述了一群德克萨斯人向艾滋病病毒发起勇敢抗争的故事。获九次金球奖提名的莱昂纳多?迪卡普里奥(Leonardo DiCaprio)因在《华尔街之狼》(The Wolf of Wall Street)的出色表现第二次摘得最佳男演员桂冠。他在发表获奖感言时感谢了影片导演马丁?斯科塞斯(Martin Scorsese)对他的指导(该片是两人第五次合作),并感谢他“允许自己跟着他拍下了这部电影”。
其中有铁环的那一个是在江苏西部的仪征市发现的。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

It is a timely warning. His findings, he writes, “point to a heightened risk of emerging market crises in the coming years as the Fed continues to normalise interest rates”.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
From the themed collection: 2014年建材加盟专业报告指南
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

最佳二人组:汤普森广场

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Set in 1950's London, Reynolds Woodcock is a renowned dressmaker whose fastidious life is disrupted by a young, strong-willed woman, Alma, who becomes his muse and lover.
约40%的创业者的大部分收入都来自自己的公司,平均薪资约为19.4万美元,而非创业者的平均薪酬为17.1万美元。亚洲和大洋洲的创业者看起来是最成功的。他们中近一半人(48%)的大部分收入都来自自己的公司,而且薪资最高(平均为25.1万美元),稍高于中东的创业者(24.4万美元)。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

安哥拉,津巴布韦,和阿尔巴尼亚的排名在所有国家中上升幅度最大。“从广度和深度上来讲,拉丁美洲,加勒比地区,以及撒哈拉以南非洲等地域的国家,人民幸福感提高比较大。腐败的减少也是提高幸福感的一个很重要的原因。”
Comparatively, the increase rate is higher than income rise of urban residents for the same time period, which is 17.4%.
苹果推出了新一代iMac 电脑,1998年5月6日,旧金山
China has all long and continues to support a united, prosperous and stable European Union, support a strong Euro, and support European integration process. We believe that is good for globalization, for a multipolar world and for diversity of civilizations. We feel optimistic about the future of the EU and the future of China-EU relations.

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

10.超敏感电子皮肤
神经系统科学家发现了小脑的一项全新功能。长期以来人们一直认为小脑基本上与意识直觉等活动无关,它的主要作用是协调站立、呼吸等基本的身体活动,然而,实际上小脑在影响人类行为上也发挥着重要作用。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

While there is a still a way to go to ensure the LGBT community has the same rights as sexual couples, the world has moved on significantly in recent years. In fact, gay marriage is now legal for 60% of Americans. What about the other 40%, you ask? The List Love really believes the rest of the United States, and many other countries across the world – we’re talking to you, Russia! -will catch up soon.
Song “The China Style”(Jiuyue Qiji)

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

这就真相了,我同意。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

上榜的12所美国学院平均而言是性别比例最为平衡的,女性学员比例为48%。
Two United States cities have seen significant increases in costs, with Los Angeles rising 19 places to enter the top 10.
中国为包括棉花、糖和玉米在内的大宗商品设置的最低价格过高,当这些价格偏离市场价格时,政府鼓励了过度生产以及强劲的进口。
这两笔交易中最大的风险在于伊巴卡和塔克这个夏天即将成为自由球员,但是失去一到两名球员的痛苦和早早的在五月就被淘汰出季后赛相比就不算什么了。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

An evaluation report on the "Double Eleven" (singles' day) shopping spree has been released in Beijing, offering insights into China's largest annual online shopping event.
Official data indicates a total of 81 feature length films, including 47 Chinese titles, surpassed the 100 million yuan box office threshold.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Mr Trump is almost a textbook demagogue.
Mr. Lyons took a casting of Ms. Swinton’s mouth and designed teeth to fit. Those were clipped on over Ms. Swinton’s real teeth. For Minister Mason, he came up with a quirky look but didn’t quite want it to be comical. He was, however, interested in adding a little bling. “There’s a little bit of gold on the left-hand side,” he said. “We used real gold to make the filling of one tooth. We did it to put more character into the character.”
在科技初创公司大会上(比如去年12月在赫尔辛基举办的Slush),各方都在讨论体验。未来一年可能会看到更广泛地采用虚拟实境(VR,让用户置身于数字化强化的环境中)和强化实境(AR,把数字信息叠加到现实世界中)来创建新的数字企业。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

新上榜品牌有26个,其中前三名为乐视、安邦和东方财富,其中民营品牌占70%。小米品牌价值涨幅最大,其价值是去年五倍,为73亿美元,TCL和华为位居其后。
然而据北京出入境边防检查总站(Beijing General Station of Exit and Entry Frontier Inspection)称,只有14,000名旅客办理了过境免签手续,远低于官方此前预计的20,000人。
麦迪逊马里奇(Madison Marriage)是会计和税收事务记者

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

希拉里的回应则迎来了掌声:"我认为我是个女权主义者,因为我相信在我们经济和社会的方方面面,女性都应该获得跟男性同样的权利,不管是在我们国内,还是在整个世界上。你们知道,我在公共生活中将大量精力投入到了为女性倡权上,通过法律、规定、文化等途径做一切力所能及的事情,改变依旧存在的、让女性退缩的那些成见。"
Marlohe will shoot the Malick film concurrently with the ongoing press tour for Skyfall.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 区域一体化催生长三角发展新动能
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

After her legal travails , anything Kesha released would have a veneer of triumph. But this comeback set was an artistic warrior cry more potent than any might've expected.
'I have to echo that, You have steel in your eyes when you sing. You are totally focused. The first time I heard this song it was fantastic, well this was a step up,’ Simon shared.
Unlike several items on this list, artificial pancreas aren't still in some early development stage. The device very much exists and got FDA approval for sale this past September.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

“Policymakers around the world are cognisant of the impact the Fed decision will have and are worried, which makes us worried,” said Simon Lue-Fong, head of global emerging debt at Pictet Asset Management. “People are saying the decision is priced in but seeing as no one knows exactly what will happen how can that possibly be true.”
Age: 44

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

I loved his list (hat tip to him), but I thought I’d elaborate on what I believe makes for an effective boss or manager。
Siddeeq现在已经是一位退休教师居住在中西部城市Indianapolis,他表示当大学联系到他的时候他震惊了。
But the economic picture has brightened considerably in Arizona, as the housing market stabilized and unemployment hit a post-recession low of 7.8% in May. As part of Forbes’ annual Best States for Business, we look at 35 factors to determine the best and worst states, including projected employment. Arizona is expected to have the fastest job growth at 3% annually over the next five years, according to Moody’s Analytics. The job gains are projected to boost household incomes 3.6% annually through 2017, which ranks second best in the U.S. after Illinois. The added jobs also go hand-in-hand with the state’s economic growth, which Moody’s forecasts to expand at a U.S.-best 4.6% annually.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

5. Starbucks. Brand love: 26% / Social Business Index Rank: 26

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
From the themed collection: 北京冬奥村赛后将变身人才公租房
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

单词global 联想记忆:
我们当中很多人都有八卦抱怨的习惯。但是如果做的太频繁的话,工作恐怕就不保了。所有的这些会带来一个同样的结果:变成了老板的眼中的麻烦。一般来讲,老板要确保自己的团队有正面的能量,团队中如果有人是消极的,会有损他的形象。消极的员工在高级管理层中被认为是“癌细胞”,这是因为“他们早晚会被割除”。如果你有怨念的话,一个好的办法就是私底下直接和老板对话。 千万不要一开始就拉拢人心寻求支持。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Meanwhile, figures such as Wang Jianlin, China’s richest man, have raised concerns about Chinese state-owned enterprises’ investments in Europe, arguing that they lack international management standards.
3. Learn from others.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

一位本田高管私下里将该公司的很多问题归咎于“运气不好”,而不是内部管理不当或有意失职。也许确实如此。不过本田管理层确实应该认真反省,反复自查,并控制好其管理系统和生产流程,确保客户好感度不再每况愈下。(财富中文网)
同时,2016年应届毕业生选择就业的比例有所上升,比例由2015年的71.2%提高到 75.6%。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

'The book is true to the character and keeps him as fans would want him, which is as the original hard-bitten guy,' he said.
These artificial ears will be a huge benefit to those who suffer injuries or who have microtia, a condition that keeps the ears from ever developing.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

又或者,今年是一群有跟虐待、性或其他有关的故事要讲的女性。她们其中几个人在我们的页面上分享了“我也是”(#MeToo)的经历。卡洛塔·加尔(Carlotta Gall)讲述了汉达·阿亚里(Henda Ayari)的故事。后者是一名拥有北非血统的法国公民,也是一名反萨拉菲派活动人士。她指控牛津大学某知名教授强奸了她。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Effective bosses must be effective decision makers. He or she cannot vacillate over every tiny decision. Being able to make decisions quickly and decisively — and then take responsibility for the outcome (see number 2) — is an important business skill, especially when managing others。
唐同学怀疑水中被混合了有毒物质,便把此事报告给班长和老师。
"China is really in a tough position," Dr. Peters said. "Emissions have grown so much in the last 10 years or so that no matter how you look at China, it has an immense task."
买securities很不security(n 安全)

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

The Man Who Knew, by Sebastian Mallaby, is the 12th winner of the £30,000 award, which goes to the “most compelling and enjoyable” title of the year.

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 北京通州启动群租房专项治理
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

adj. 荒谬的,可笑的
Alumni from the Swiss school also have the third-highest salary, at $114,449, adjusted for purchasing power parity, behind those from the Indian Institute of Management at Ahmedabad, on $116,476, and IIM Bangalore, on $116,094. St Gallen is also top for the quality of its careers service.
Company: Eventbrite

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

大隅在自噬作用上的研究成果,为帕金森病、糖尿病等常见疾病的治疗带来了一线希望。
n. 全体船员,全体乘务员,(一组)工作人员

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

25 July
Song “Beautiful China”(Sha Baoliang and Xu Qianya)

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

[k?n's?lt]

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

北京大学和北京外国语大学的2017届毕业生平均月薪分别为9042元和9020元,位居第二、三位。
《我无法忘记那天晚上和他在一起时发生的事》(‘I Could Not Forget What Happened to Me That Night With Him’)
Fifteen Chinese nationals have been charged with developing a fraud scheme in which they paid imposters to take entrance exams, including the SAT, and gained acceptance to elite American colleges and universities, the US Department of Justice said on Thursday. Conspirators were paid up to $6,000 each time they used counterfeit Chinese passports to trick test administrators into thinking they were the person who would benefit from the test score, a federal grand jury charged.重点单词

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

因为一种鲜为人知的病毒所造成的重大影响,2016年将在全球卫生方面被人们铭记。这似曾相识,不过此次登上全球头条新闻的不是埃博拉病毒,而是寨卡——一种通过蚊子传播的病毒,大脑存在缺陷的新生儿数量在巴西急剧增加与此有关。
2. 麦嘉华对贝南克灾难性QE计划的末日警告
“还有大批人没有统计进来,”胡润对英国《金融时报》表示,“两周前我在北京拜访了这家投资公司。一下午的时间,我就发掘出了30个登上今年富豪榜的人。他们去年还不在我们的视线内。”
Social networking platforms, including Weibo and mobile app WeChat, proved to be the best tools for cyberstars to magnify the power of communication, making it possible to create an industry that combines advertisements, e-commerce and fans.

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

根据全球最大航运公司马士基航运公司(Maersk Line)的数据,从汽车到集装箱运输的纺织品,1月中国对巴西出口同比下降60%,而通过集装箱进入拉美最大经济体的总进口量减半。
Hilcorp Energy:能源公司的个性化奖励

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

该排行榜为有工作经验的高级管理人员评出全球最优秀的100个EMBA项目。
2013年,勇士队曾在中国与洛杉矶湖人队打过季前赛,而森林狼队则是首次来华。
['vid?il?ns]

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
156 items - Showing page 1 of 3

About this collection

信息技术是第三大行业,有18个入围品牌。上榜IT品牌的总价值占到了榜单的22.5%.平均价值上升了10%。北京是IT行业总部的首选位置,有12个上榜IT品牌的总部设在这里。
Maddie is so well recognised these days that a trip to Topshop results in her being mobbed by screaming tween fans who all want a selfie with their idol - something that has been tough to adjust to.

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