Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
In early December, authorities announced that market circuit breakers would be introduced become effective from January 1 in an effort to limit the volatility seen during the savage, summer sell-off from June. The circuit breakers would see trading in shares, options and futures halted for 15 minutes if they fell by more than 5 per cent. On their first day of use, that first threshold was breached just after the return from the lunchbreak, prompting a 15-minute halt.
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Those concerns are casting a heavy shadow over a two-day meeting of G20 central bank governors and finance ministers due to start tomorrow. The International Monetary Fund this week already warned that it was poised to downgrade its forecast for global growth this year, saying the leading economies needed to do more to boost growth.
Trends and targets in antiviral phototherapy
Average years of work experience: 12 years
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
After an investigation, Rongchang police arrested Zhou on April 29 for endangering public security, according to the Chongqing Morning Post.
Novel biosensing methodologies for ultrasensitive detection of viruses
Exports to both South Korea and Asean countries fell by about 3 per cent, however, while those to re-exporter Hong Kong dropped by more than 16 per cent.
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
Diagnostic technologies for COVID-19: a review
Best Companies rank: 68
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
While the political system will be fixated on preserving stability as new leaders take the helm, reduced economic flexibility could thwart Beijing's intentions to do so.
4.You Don't Like Most of Your Coworkers
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
6. 《出租车》(Taxi)，导演贾法·帕纳西(Jafar Panahi)。
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
新年英文祝福语大全Best wishes for the year to come! 恭贺新禧！ Good luck in the year ahead! 祝吉星高照！ May you come into a good fortune! 恭喜发财！ Live long
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Antiviral drug discovery: broad-spectrum drugs from nature
Guangzhou and Shenzhen, benefiting from balanced development, took first and second place respectively in the rankings. Hangzhou ranked third, owing to its technological advantages. Wuhan, which had achieved a good balance between development and costs, was in fourth place, followed by Nanjing with its quality culture and lifestyle.
So many are tuning out. Denial. Truth is, bubbles are everywhere. Ready to blow. The evidence is accelerating, with only one obvious conclusion: Max 98% risk at a flashpoint. This 2014 crash is virtually guaranteed. There's but a narrow 2% chance of dodging this bullet.
Influenza neuraminidase: A druggable target for natural products
We should stipulate at this point that neither of us have any idea how good this draft is going to be because the college season is barely underway. It sure looks nice, what with all those freshmen stacked up together in the lottery.
Welcome, and before we begin – please accept our apologies. Your four-hour nightmare wait at passport control should not be taken as a symptom of Britain's contempt for foreigners. It is merely a symptom of a woeful lack of spending on a key aspect of travel infrastructure in the run-up to a hugely important event. In other words, it's the government that hates you. Don't worry, they hate us too.
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
We will strive to boost employment and business startups.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
As fall arrived and school began, D'Aloisio felt immense pressure to deliver for his backers. He needed to whip his algorithm into better shape, so he contracted a team of Israeli coders who specialize in natural language processing. Searching on Google, he found and hired a retired professor living in Thailand who'd written seminal books on the topic. 'He became our main scientist,' says D'Aloisio. 'He now works at Yahoo! in the Sunnyvale office.'
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
o Outside events can intrude.Consumer Reports, which raved about the Model S, reported a few “quirks” recently that included door handles that failed to activate and a center touch screen that went blank, blocking access to most of the car’s functions. Edmunds.com has had trouble with its Model S too. More reports like that will dent Tesla’s heretofore shining reputation.
China and its southern neighbour failed to come to an agreement on cross-border trade last month during Vietnamese president Truong Tan Sang's state visit to China, where he met with his counterpart Xi Jiping.
"This year's prize concerns a central economic problem: how to match different agents as well as possible," the academy said.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Last year, the General Administration of Quality Supervision, Inspection and Quarantine conducted random quality inspections on 1,013 batches of such products, including consumer goods such as toys, paper diapers, clothing and kitchenware, with 415 found to be substandard, accounting for 40.9 percent of all sampled products, according to Han Yunping, spokesman for the administration.
Despite the huge production, the focus was on the 40 gorgeous models who walked the runway.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
最佳综艺小品：帕顿?奥斯瓦特(Patton Oswalt)，《帕顿?奥斯瓦特：为掌声而鸣》(Patton Oswalt: Talking for Clapping)
It seems that Christmas time is here once again, and it is time again to bring in the New Year. We wish the merriest of Christmas to you and your loved ones, and we wish you happiness and prosperity in the year ahead.又该迎接新的一年了。我们向你及你的亲人们致以最美好的祝福，愿你在新的一年里事业兴旺，幸福美满！
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Stanford's Zhenan Baohas has developed a super-flexible, super-durable, and super-sensitive material that can be the basis for future synthetic skin. People have tried developing synthetic skin before, but Baohas's material handles touch sensitivity better than any predecessor. It contains organic transistors and a layer of elastic, letting it stretch without taking damage. And it's self-powered—this skin contains a series of elastic solar cells.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
"Wholesale food prices suggest that pork, vegetable and fruit price inflation all eased last month," said Capital Economics before the figures came out. "
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
PRICE PER SQUARE FOOT: $667
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
10. China watchers inthe United States will continue to postulate China’s declining growth rate inthe face of evidence that it is stable at over 7%. China will grow fasterin 2014 than in 2013.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Succeeding as an entrepreneur takes hard work and persistence because, unfortunately, there is no business-startup fairy who magically bestows success on small businesses and their owners.
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Second, McDermott, a career 39.9% three-point shooter, addresses Oklahoma City's biggest roster weakness—a lack of perimeter options around Russell Westbrook—and remains on a bargain rookie deal through the end of next season.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Slice stems at a 45 degree angle.This leaves a larger exposed area so blossoms can absorb as much water as possible, and also allows stems to stand on point, s
Total Program Cost: $181,500 in either Philadelphia or San Francisco
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
圣加伦大学校友的薪资排名第三，为114449美元（按购买力平价调整后），排在艾哈迈达巴德的印度管理学院(Indian Institute of Management)和印度管理学院班加罗尔分校(IIM Bangalore)之后，这两所商学院校友的平均薪资分别为116476美元和116094美元。圣加伦大学还在职业服务质量方面排名第一。
根据花旗居屋(Citi Habitats)提供的数据，在布鲁克林拟于明年投放市场的6527套新出租屋中，有1442套分布在贝德福德-斯图文森(Bedford-Stuyvesant)、布什维克(Bushwick)和克林顿山(Clinton Hill)。就在不久前，这些社区都还被视为不热门的地区。
China's consumer price index (CPI), a main gauge of inflation, rose by 1.6% in 2017, lower than the yearly control target of 3%, the National Bureau of Statistics (NBS) said on its website.
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
The gig economy
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
圣保罗报的民意调查是基于在贝洛奥里藏特（Belo Horizonte）的米内朗球场（ Mineirao）对693名球迷进行的采访，统计误差为4%左右。
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
After rising every year since 2008 global gold supply plateaued last year, according to the World Gold Council. In China, the world’s biggest producer, it fell by a record 9 per cent, the second time output has fallen in the country since 1980.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
In a separate report in early September, the World Meteorological Organization said the level of carbon dioxide in the air in 2013 was 42 percent above the level that prevailed before the Industrial Revolution. Other important greenhouse gases have gone up as well, with methane increasing 153 percent from the preindustrial level and nitrous oxide by 21 percent.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
The fastest-rising sector is apparel, driven by Nike in sportswear as people pay more attention to health and fitness, and Zara, whose fast fashion is becoming increasingly popular in China.
Bigcommerce does particularly well among small retailers generating $1 million to $2 million in annual revenue, although its following with those in the $20 million to $30 million range is growing quickly. Roughly 70% of its existing customer base also runs a bricks-and-mortar store. For the past year, the developer has worked hard on responsive storefront templates that work equally well on mobile platforms and desktops—design is the number-one consideration for small e-commerce merchants, it says—and on relationships with partners of “adjacent” cloud services from the accounting, payments, customer relationship management, and payroll management worlds.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Season\'s greetings and sincere wishes for a bright and happy New Year!
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
These were no lightweight pundits. The eminent historian Margaret MacMillan, in an essay for Brookings in December 2013, said, “We are witnessing, as much as the world of 1914, shifts in the international power structure, with emerging powers challenging the established ones.” She added, “the same is happening between the US and China now, and also between China and Japan”, and also said that “there is potential for conflict between China and two of its other neighbours — Vietnam and Malaysia — as well.”
"We hope the mother will come to us and verify the facts. If it's true that the user is a 13-year-old who spent the money without consent, we can negotiate a refund," the Tencent employee said.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Rather than strangling the doctor (difficult, due to his injury) Jalava took the corny line as inspiration. He decided to go ahead and actually build a prosthetic finger that contains two gigabytes of digital storage. He can now jack his finger into a computer just by peeling back the nail to expose the USB plug. He can also remove the entire finger at any time and hand it to a friend to use.
As we ring in the New Year, let’s take stock of where we are at with the oil markets. 2014 proved to be a momentous one for the oil markets, having seen prices cut in half in just six months.
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
But Michael DeFranco, chair of Baker & McKenzie’s M&A practice, hailed the Chinese group’s investment in developed economies.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
As for Dirk, nobody should ever go out the way they do, but it happens all the time. In some ways, maybe it's easier if the reckoning is this painful.
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
警方在屋内查出一柄40口径的Smith & Wesson半自动手枪，目前正在进行弹道测试，检查器是否牵涉其他犯罪活动。
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
The Asia-Pacific region was the main driver of international growth at movie houses, up 13%, and China accounted for nearly half of the entire Asia-Pacific total.
Issued by the Institute of Social Security Research, Ministry of Human Resources and Social Security, the report shows that the return rate of enterprise employees' pension insurance fund reached 3.1 percent, the highest in seven years.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
7.M·A·S·H Star Never Signed his Contract
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
For: Since it premiered at the Venice Film Festival, it's being wowing audiences.
While China remains the largest holder of American government securities, it cut down exposure to USD 1.25 trillion in October.
Will China's stock market climb back to the 6,000-point mark it reached two years ago? The stock market was at its most bullish back then, but if you ask the same question now, some would cite a global economy still reeling from a recession.
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
China produced an estimated 420.5 tonnes of gold last year, according to the World Gold Council. Over the same period, Chinese demand for gold rose by 4 per cent to 953.3 tonnes, it said.
Some smart beds will promise you better sleep and posture, but this one in particular will turn you into a private investigator looking to catch a cheating spouse in the act. Regardless of knowing if it's comfortable, the Smarttress alerts you "whenever someone is using your bed in a questionable way."
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
而其他的队伍还有在尝试赢球的。小牛队，在3-13的战绩面前，骄傲地说他们不会垫底。但是，明年被认为是近年来最好的NBA选秀，有Markelle Fultz, Jayson Tatum, Lonzo Ball, Josh Jackson, Harry Gile, OG Anumoby, Ivan Rabb……等等优质球员。
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Bringing harmony to Apple’s internal fiefdoms has not been easy. There is still “huge tension” inside Apple, according to one person who has worked with the company for many years. “That tension is something he uses to run the company but it can be dangerous.”
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
9. 《大空头》(The Big Short)。亚当·麦凯(Adam McKay)把影片处理为喜剧，但在他以笑声轰炸屏幕的同时，也表明他对这场2008年经济崩溃的呈现是一场让人心碎的美国悲剧。
Anti-HIV drug repurposing against SARS-CoV-2
If he wins the primary, he would face off against first-term Republican Gov. Phil Scott, 59.
Length-scale dependence of protein hydration-shell density
6、Social media addiction
Why does beauty exist? To answer this question, Richard O. Prum, an ornithologist, is working to revive an idea advanced by Charles Darwin: the attractiveness of an animal to another of its species isn’t only tied to fitness and good genes. Rather, animals — especially birds in Dr. Prum’s work — are making subjective decisions. He hopes that evolutionary biologists will stop “explaining away desire.”
里奥斯工作非常努力。她很小的时候就从萨尔瓦多来到了美国。以优异成绩从高中毕业后，她一边养家，一边读完大学。成立Nation Waste Inc.公司的时候，她并没有感到害怕。22岁的时候，里奥斯刚刚从休斯敦大学（the University of Houston）毕业几个月就贷款购买了两辆卡车，毅然投身由男性主导的垃圾处理行业。目前，这家位于休斯敦的公司有24名全职员工。里奥斯说：“回头看看过去的经历，总是让我感到吃惊。我很小的时候就跟着父母来到美国，现在我正在实现我的美国梦。”
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
Moreover, a “turnaround in the short run is unlikely”, given China’s efforts to rebalance its economy from exports towards consumption (thereby reducing demand for imports of intermediate inputs), reinforced by “government policy to stimulate the use of domestic suppliers” and rising protectionism elsewhere, he argues.
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Gunmen kidnapped 18 Turkish workers Wednesday in Iraq's capital.