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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

这篇文章发表后,美国参议院很快投票通过了《反就业歧视法》(Employment Non-Discrimination Act)。这样,在工作中歧视LGBT群体也有可能成为违法行为。这项法案即将提交众议院审议。
单词muscular 联想记忆:

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Skyfall Bond girl Berenice Marlohe has joined the all-star cast of Terrence Malick’s latest movie, which is in production in Austin.
马自达获得了最佳轿车品牌的称号。汽车媒体一直很青睐马自达的表现,而如今的马自达汽车都在精致的内部设置和强大的驱动力上赢得了积极的反馈。上图的2016马自达第三代,在美国新闻小巧车排名中摘得桂冠,它的精准操控,强大加速度和高端室内布局,赢得了大多数汽车评论家称赞。

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

It’s no surprise that credit is “pro-cyclical.” When asset prices are booming, optimistic lenders tend to make more loans and often feed the euphoria. When markets sink, lenders rein in risk and sometimes make the downturn worse.

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

'If you read Trigger Mortis, you’ll see actually there is a little twist to the tale in that particular story which I think sort of pays him off for his slightly patronising attitude.'

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

In a separate report in early September, the World Meteorological Organization said the level of carbon dioxide in the air in 2013 was 42 percent above the level that prevailed before the Industrial Revolution. Other important greenhouse gases have gone up as well, with methane increasing 153 percent from the preindustrial level and nitrous oxide by 21 percent.
vt. 建议,推荐,劝告
Dafoe is probably the current front runner for best supporting actor.
The Shanghai Composite is nursing a decline of 6.85 per cent, while the tech-focused Shenzhen Composite is down 8.19 per cent.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

别让自己工作得太舒服
以下是我们精选的本届科隆游戏展最值得关注的新游戏。
1.水上类比赛项目
凡是这家汽车服务公司的忠实员工在效力满10年后,都可获得一份奖励:在佛罗里达州波卡拉顿的一处度假胜地欢度周末(此地距该公司总部仅15分钟车程)。这项福利此后每5年都可以享受一次。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

n. 运输,运输系统,运输工具

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

As consumers in developing countries continue to shift to meat-based diets, grains and oilseeds used as livestock feed are expected to see support.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

目前已经被泄露的照片多达10个G。据《北京日报》12月1日报道,著名在线P2P借贷平台"借贷宝"也和此次事件有关。
The strategy of Four comprehensives: Comprehensively building a moderately prosperous society, comprehensively driving reform to a deeper level, comprehensively governing the country in accordance with the law, and comprehensively enforcing strict Party discipline

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

"In the aftermath of recessions, there's always a period of jobless recovery," says John Challenger, CEO of global outplacement firm Challenger Gray & Christmas. "We're certainly not optimistic about seeing much improvement in the unemployment rate in 2010."
当时,Spielman正在耶路撒冷Emek Tzurim国家公园橄榄山的斜坡上检查泥土。突然就注意到了这个小小的矩形物件。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

“有个人请妻子跟自己老板打电话说他不会再来上班了。”
学员非常有经验,一位毕业生说,所有学员之间的交往和互动是这个项目的重要方面。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

在《醉乡民谣》(Inside Llewyn Davis)中,编剧兼导演乔尔?科恩(Joel Coen)和伊桑?科恩(Ethan Coen)兄弟俩挥之不去的忧伤情绪转化成了令人难忘的戏剧性场面。我觉得我的评论本应澄清,这部关于流行文化牺牲品的悲歌有一种特别的味道;其中一些部分相当阴郁。奥斯卡?伊萨克(Oscar Isaac)在片中出演一位自暴自弃的民谣乐手,宿命般地献身于他的艺术,他的卓越表演令这部影片极其震撼人心。
《X战警:天启》据悉将于2016年5月27日上映。
[ru:t]
IT/通信/电子/互联网行业的应届生签约最高月薪为4867元,同比去年下降826元;紧随其后的是金融业和交通/运输/物流/仓储行业,平均签约月薪分别是4692元和4457元。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
From the themed collection: 小众市场兴起民宿客栈业商机乍现
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

伦敦时装周将不会在今年的T台上展出任何使用动物皮草的服装或配饰,使其成为第一个无动物皮草的主要时装周。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

A lighthearted rom-com starring Adam Sandler and Drew Barrymore is the last thing you'd expect to mirror real life, but this comedy was in fact partially based on a true story. Sandler plays a veterinarian who falls in love with Barrymore, an amnesiac whose memory resets at the beginning of each day. He learns that Barrymore has replayed the same day over and over again since a car crash left her with a traumatic brain injury. Upset by the lie she has been living, Sandler's character makes a series of videos that explain her accident and her life for her to watch each morning.
2. "Breaking Bad" (4.2 million)

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

工业生产者出厂价格指数(PPI)通常被认为是中期通胀的代表,该指数仍留在负值区间,但下降速度有所放慢。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

女士们、先生们,欢迎来到2016年没礼貌大奖颁奖典礼。

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Blake Griffin's high school appearance isn't that far off from how he looks today. Just add some hair and some size to his biceps, and you've got Blake Griffin today.
比特币区块被讨论得最多的一项潜在用途,是去中心化的打车服务“Uber”。客户无需使用特定软件,就能订车并直接向司机付款,去掉中间商。(Uber创始人特拉维斯o卡兰尼克,抱歉)区块能用于各种用途,从储存安全文件(去中心化的的Dropbox)到“水印”技术,水印技术是指某块特定的比特币能包含比如你房子的房契。Digital Currency Group投资主管赖安o希尔基斯表示:“区块将催生数十年的创新。这可能催生零阻力股票发行、所有权转让以及智能合同。而上述事物共同构成了经济的支柱。如果你想创建分散管理的优步、Dropbox以及Facebook,你可以重塑互联网。”Digital Currency Group由前SecondMarket创始人巴里o希尔伯特创办。
['pri:dises?]
哈佛大学发言人瑞秋?戴恩拒绝对该新闻发表评论。她在邮件中写道:“我们对于个别申请人的录取情况不予置评”。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Opening up
Another love ballad for Bond, but if Nancy Sinatra's song from You Only Live Twice was playing at your orthodontist's office, it would be the sexiest orthodontist's office in town. There's a mysterious quality to the string section, and a playfulness to the declining notes. They combine to make something rather magical. From here on out all of the Bond songs on this list are bona fide classics.
对民主主义者而言,此类原始情绪的爆发之所以令人担忧是因为它们很难遏制。
节目35 歌曲《美丽中国》,沙宝亮 徐千雅
英国新人结婚模仿“怪物史瑞克”(图)

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

That is up from a rise of 11.2 per cent in September.
Jack Ma, founder and executive chairman of e-commerce giant Alibaba Group topped the ranking of China's richest IT people for the third consecutive year.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

1. Smart mattress

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
From the themed collection: 软体家具污染源解析
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

The rise of ephemeral social networks

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

The United States saw its real GDP increase at an annual rate of 3.9 per cent in the three months ended September,according to official data released last month.
o Battery power may turn out to be a transition technology. Cost reductions have been slow in coming, and Tesla needs a 30% improvement in order to build the $35,000 Model 3 it has promised for 2017. Toyota’s recent move was eye-opening. It is allowing a battery-supply deal with Tesla to expire and instead will redouble its work on hydrogen fuel cells. The cost of fuel cells is coming down faster than batteries and fuel cell proponents believe drivers will prefer a relatively rapid refuel with hydrogen to waiting hours to recharge their batteries.
It's impossible to list every woman who's ever existed, this list obviously be restricted to women who've achieved a fair level of celebrity. These are the hottest women celebrities of 2015.
AR could be the bigger opportunity after Apple’s Tim Cook gave the technology his backing — it was included in Apple’s latest operating system and its iPhone X device.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

中美两国人民都是伟大的人民,我们有智慧来管控分歧,我们有需要也有条件来扩大共同利益。
There are legitimate reasons to doubt that Nerlens Noel can blossom into a dependable starting center, including his injury history, off-court red flags, and extremely limited offensive game.
大多数企业家(78%)利用储蓄或依赖朋友和家人来筹集全部或部分启动资金。四分之三的企业家也使用天使融资来作为资金来源。
5.品牌推广:增长了16.4%

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

亚洲的商界女性在崛起:整个亚洲地区在榜单上的表现都非常抢眼,从中国和新加坡到新西兰和泰国,都能找到女强人的身影。亚洲的女性企业家群体正在崛起,例如张欣(排名第50)、孙亚芳(排名第77)和周凯旋(排名第80)。在政界,亚洲女性也在施展自己的抱负,例如新上榜的韩国总统朴槿惠(排名第11),缅甸反对派领袖、国会议员昂山素季(排名第29),澳大利亚总理茱莉亚·杰拉德(排名第28),以及泰国总理英拉·西那瓦(排名第31)。
制定计划

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

Industrial production expanded 1.4 per cent month-on-month in October, the quickest pace since a 4.1 per cent rise in January. It was better than the 1.1 per cent gain in September, but still fell short of economists' expectations for a gain of 1.8 per cent.
Statistics showed that Tibet had around 590,000 rural poor by the end of 2015.
单词population 联想记忆:
2、《蝙蝠侠大战超人:正义黎明》
Cousins's deal qualifies as a blockbuster, the Raptors made two strong moves to bolster their contender status, and the race for the West's last playoff spot got far more intriguing, among other storylines.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

One year after new measures were implemented, Shanghai saw a year-on-year increase of six times the number of permanent residence applications from foreigners and their families.
The joint programme delivered by Tsinghua and Insead University (Tiemba) moved up two places to lead the 2015 global executive MBA ranking, dethroning Trium, which drops back to third place after only one year at the top.
可口可乐正在改组其业务,出售其在美国以及全球的瓶装业务,转而专注于生产其很多饮料使用的浓缩汁,以及研发。这些资产出售将让该公司将更多资源投入创新和收购。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

7月,中国政府首次尝试规范互联网金融,央行、银监会、证监会等10家机构联合发布指导意见,提出了“互联网金融”的官方定义,并明确了各机构负责监管的互联网金融机构类型。
该片根据同名童话故事拍摄而成,主要讲述了主人公毛各利的丛林奇遇,他试图在探险中发现自己。他在丛林中遇到很多生物(由众多演员扮演),正是这些生物使他的旅程变得异常艰辛。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

The awards returned Ms. Lawrence, a winner last year for Russell's 'Silver Linings Playbook,' to the stage for an acceptance speech-something she said was no easier a year later.
Concerns about the vulnerability of some emerging economies and gyrations in financial markets over the past few days should not dent “cautious optimism” about the global economy this year, leading central bankers and officials said on Saturday.
It is revealed that Hadid's visa application was turned down after she offended many by squinting her eyes in an attempt to impersonate the Buddha in February.

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

FOYLE’S WAR (acorn.tv, Feb. 2) After nabbing the final three episodes of “Agatha Christie’s Poirot” last year, the streaming service Acorn TV scores another coup in the field of traditional British mysteries with the American premiere of this superior show’s ninth season. Starring Michael Kitchen as Christopher Foyle, a detective as honorable as he is shrewd, the series has morphed over the years from a provincial home-front cop show to a le Carré-like Cold War thriller. New episodes involve the Nuremberg trials and Britain’s role in Palestine.
这些情况眼下一个都不存在。去年12月开始的美联储政策紧缩已经暂停。联邦基金利率(银行间隔夜拆借利率)估计低于自然利率逾一个百分点。美联储一直未作出意外之举。例如,美联储去年12月将政策利率提升25个基点之前发出了大量信号。
"It is a massive jump in very little time: there were just about 30 cases when I became interior minister (in mid-2012), and 1,400 today," said Valls.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 家纺行业挤泡沫 企业扩张放缓
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

但是Gitanjali的便携发明,可以通过一个与手机app连接的传感器,就得出一个确切、及时的分析。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

排名:第一

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

['limitid]
Four factors should fuel the jobs recovery in 2013:[qh]

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

Mr Koepke warns that this could easily be upset by the Fed.
埃尔多安表示,德国总理安格拉?默克尔(Angela Merkel)“与荷兰没有什么不同”,并敦促移居海外的土耳其人不要在即将到来的欧洲选举中投票支持“现任政府和种族主义者”。要在今年9月成功竞选连任,默克尔面临一场硬仗。
James Bond Themes 3. "Skyfall" by Adele
Hilcorp Energy:能源公司的个性化奖励

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

想要工作稳定,最重要的是你与老板的关系。即使他跟你说:“我很想留住你,但是他们一定要让我辞退你。”这很有可能是假话。他才是那个下决定的人。
但如果美国能够避开由华盛顿造成的这一危机,明年劳动者找工作的前景实际上还相当不错。首先,超级飓风“桑迪”(Sandy)造成的破坏将需要修复,这样就会带来建筑业和零售业的工作机会。与此同时,因为财政前景的不确定性而暂停投资和招聘和企业可能最终打开钱包。这也意味着会有新的就业机会出现。[qh]

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Note that grosses are not the same thing as earnings. Downey outearned Johnson by $29 million with $75 million in estimated earnings between June 2012 and June 2013, the period we used for the latest edition of our Celebrity 100 list. The numbers we’re looking at here are how many dollars each star’s movies brought in at the box office worldwide this year.
[slaut?]

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

不过巴蒂表示,中国大学排名的稳定并不值得担忧。他说:“数十年的持续投资建设以及中国高等教育国际化程度的提高,无疑将使得中国的大学变得越来越好。”

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

[k?n'tein]
Be prepared to save his life on numerous occasions.
问:你今年夏天去了美国,感觉怎样?
"I heard from several business leaders who shared their concern about our relative silence and impact in urging the political leadership to act on behalf of the citizenry," Schultz wrote in a letter on his company's website.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 建材行业如何化解品牌难题
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

为了解决上述问题,报告建议应尽快制定电子商务法。同时,该报告还呼吁应建立一个在线信用体系,以此加强对电子商务行业的纪律监督。
1.苹果。 品牌喜爱度:57%/排名:32

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Spielman was sifting through dirt at the Emek Tzurim national park on the slopes of the Mount of Olives in Jerusalem when she noticed the small rectangular object.
1999年中国航空工业第一、第二集团公司(之后两者合并为中国航空工业集团公司)的成立标志着中国开始进军商业航天领域,显示了中国迈向这一行业的绝心与意志。但实现这一雄心的脚步并不那么平坦。20年之后毫无疑问中国已经成为了大型商用航天领域的成熟玩家,将其他几国远远甩在身后,并有望打破空客和波音的长期垄断。
['b?:lru:m]

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

每天向大家推送短小精悍的英语学习资料.
The clip, taken on a mobile phone, starts with the crowd singing the Frankie Valli lyrics: You're just too good to be true, can't take my eyes off of you'.
n. 石油

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

The blocks of flats which were up to 12 storeys high in the city of Wuhan are making way for a huge new business district including a 707-metre tall skyscraper.
以下是人们经常用来描述自己的一些句子。

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
From the themed collection: 北京购房市场回温 改善置业走俏
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
From the themed collection: 厦门促进卫浴产业升级措施出台
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

Five development concept of innovation, harmonization, green, openness and sharing
It is the first time that news came up first since the technology company began publishing its yearly review a decade ago.Vera Chan, the company's senior editor and web trend analyst, said the BP oil spill was the most searched topic for term for a variety of reasons.
但1998年的记录现已被每四、五年一次的新记录多次打破,而2014年的记录是在没有显著厄尔尼诺现象发生的年度创下的。加文·A·施密特(Gavin A. Schmidt)是位于曼哈顿的美国宇航局戈达德太空研究所的所长,他说,下一次的强厄尔尼诺现象可能会打破所有的温度记录。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

昨天,中国一次控制爆破让19栋楼在10秒钟之内被夷平。
动词limit的过

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

中国旅游研究院国际旅游研究所(Institute of International Tourism)副所长蒋依依认为,外国游客数量下降的部分原因在于人民币的升值。
And, men are 2.8 times more likely to use this obvious phrase than women.
St. Vincent “Digital Witness” (Loma Vista/Republic)

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

2. Staying too long in a job that you want to leave

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

What dangers does the Fed present to EMs today? One of the biggest risks, says Mr Koepke, is that it might “get behind the curve” and delay raising rates for too long. This would result not only in a surprisingly big hike when it came, but also a higher terminal interest rate than would otherwise be the case.
由于制度是在专制统治下制定的,那么反对派就会被迫反叛或者顺从。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

Call Me By Your Name
鉴于FIFA世界杯将于2018年在俄罗斯举办,届时的旅游成本会大大提高,所以选择在2017年去可谓是明智之举。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

Although various public incentives exist, many come in the form of tax breaks, low-interest loans or rebates. So a building might have to levy an assessment or raise maintenance to cover initial costs. “You run into the problem of nobody giving you the money upfront,” Mr. Luxemburg said.
Thirty-six Chinese brands have made it onto the list this year. Among them, eight are in the top 100, including the State Grid Corporation of China (36), the Industrial and Commercial Bank of China (ICBC) (40), Tencent (43), China Central Television (CCTV) (62), Haier (76), China Mobile (79), Huawei (81) and Lenovo (90).

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
From the themed collection: 金融街:资管业务亮点纷呈
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

To start with, a year before the first iPhone was released, LG had introduced a full touchscreen phone. Even that was not the first, though. The world's first touchscreen phone was IBM's Simon, which was released in 1992. And touchscreen technology even predates the Simon. The first touchscreen device was a tablet made by E.A. Johnson in 1965 that was used by air traffic controllers until 1995. Bent Stumpe and Frank Beck made the first capacitive touchscreen in the early '70s. Unlike Johnson's tablet, it could not be pressed with the fingers. Instead, it required a stylus. In 1971, Samuel Hurst developed the first resistive touchscreen, which he called the "elograph." It responded to the fingers as well as a stylus. In 1985, HP invented the world's first touchscreen computer, called the HP-150. In 1993, Apple also released its first touchscreen device—the Newton Personal Digital Assistant. The product was a flop, recording low sales.
DeMarcus Cousins, Serge Ibaka and Lou Williams were all dealt in advance of Thursday's 3 p.m. ET deadline, leaving role players like Taj Gibson and P.J. Tucker as the biggest names to move right before the buzzer.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 武汉家居大牌时代加速来临
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

另一名学员表示:这个项目让我的事业获得了巨大飞越,为我在毕业后马上就担任一个战略最高层管理职位做好了准备。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

People who are skeptical about this argument just need look at smartphones and personal computers, which have served as the technological driving force of the past century.
That is changing. One big 2013 move for benchmark Brent crude came in August, when international intervention in Syria seemed increasingly likely. But while the price of Brent, which is traded on London's IntercontinentalExchange, did rise by 5% on the threat of U.S.-led airstrikes, it didn't come close to the 2013 high.
About 9.8 percent of the graduates are opting for "slow employment", meaning they will spend some time traveling, staying with their parents or waiting for opportunities to start up a business before figuring out their future plans, according to the survey.
Lori Steele

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

2005年初,斯通和其联合创始人爱丽莎卡玛赫特和朱瑞德斯贾丁斯发现,使用博客的女性规模庞大,但主流媒体却很少会引用她们的文章。于是,三人决定召开一次草根会议,并吸引了谷歌和雅虎(Yahoo)等赞助商。门票很快销售一空,不久,她们便成立了BlogHer.com。这个博客发布平台把撰写博客变成了许多女性可以用来赚钱的一项业务——2009年至2012年期间,这家公司向5,000名博主支付了超过2,500万美元。目前,这个平台的用户已经超过9,200万人。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

节目23 《直通春晚》①《山路十八弯》(表演者:阿普萨萨)②《我是一只小小鸟》(表演者:许艺娜)③《我爱你中国》(表演者:平安)
居民消费价格涨幅3%左右;
Chris Paul

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

沃尔玛美国公司总裁兼首席执行官比尔西蒙
持续推进大众创业、万众创新。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The relocation is also part of the integration plan for the Beijing-Tianjin-Hebei cluster, which aims to ease congestion in the capital and achieve more balanced development in the region.
随着中国实力的抬升,其最好的友敌美国占了前10名的另一半。第5名和第9名分别是伯克希尔哈撒韦保险公司以及富国银行,这两家公司相较去年的排名均上升4位。

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

4、优衣库事件

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

我经常生气
We will explore new forms of social governance.
所有这些合数值都比去年同期高,其中市场价值增幅最大(比去年同期增长13%)。这些公司在全球总共雇用了9000万人。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

9月28日
The overall 2018 ranking encompasses more schools than ever before – 1,250 universities located across 74 countries. This is an increase from the 1,000 schools in 65 countries included in last year's edition.
CONTACT: Kathy Michalove, Seaboard Properties, (860) 535-8364; seaboardpropertiesre.com
请尊重一下那些支持你的人以及节目主持人,能在访谈开始前把口香糖吐了吗?

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

She was also recognised for being the youngest recipient of the Ripple of Hope Award from the Robert F. Kennedy Center for her charity work.
The Martian was named best comedy or musical motion picture.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 家具外观专利维权纷争再起
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

When you post your résumé to a job board, such as Monster or Indeed, there's a chance your current employer could see it. In fact, Foss says many HR staffers and managers regularly search for their company names within job board submissions specifically to see if their employees are looking for jobs。
To tackle the problems, the report suggests that e-commerce laws should be developed as soon as possible. It also calls for the establishment of an online credit system to strengthen the discipline of the e-commerce industry.
posture

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
From the themed collection: 销售率不足4成 限房价项目压力大
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制造业表现较好,利润增长6.5%。受低廉的能源价格的提振,电力、热力、燃气及水生产和供应业利润增长17%。
A candidate's age is no gauge of their effectiveness, Sonneborn tells PEOPLE, saying that despite Donald Trump being the oldest person elected to the U.S. Presidency, “He tweets like a kindergartener.”

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